6-Bromo-1,2,3,4-tetrahydro-2-quinolinecarboxylic acid methyl ester - Names and Identifiers
Name | methyl 6-bromo-1,2,3,4-tetrahydroquinoline-2-carboxylate
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Synonyms | 6-Bromo-2-methoxycarbonyl-1,2,3,4-tetrahydroquinoline Methyl 6-bromo-1,2,3,4-tetrahydro-2-quinolinecarboxylate methyl 6-bromo-1,2,3,4-tetrahydroquinoline-2-carboxylate Methyl 6-bromo-1,2,3,4-tetrahydroquinoline-2-carboxylate 6-Bromo-1,2,3,4-tetrahydro-2-quinolinecarboxylic acid methyl ester 6-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE-2-CARBOXYLIC ACID METHYL ESTER 6-Bromo-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid methyl ester 2-Quinolinecarboxylic acid, 6-bromo-1,2,3,4-tetrahydro-, methyl ester methyl 6-bromo-1,2,3,4-tetrahydroquinoline-2-carboxylate hydrochloride
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CAS | 511230-72-1
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InChI | InChI=1/C11H12BrNO2/c1-15-11(14)10-4-2-7-6-8(12)3-5-9(7)13-10/h3,5-6,10,13H,2,4H2,1H3 |
6-Bromo-1,2,3,4-tetrahydro-2-quinolinecarboxylic acid methyl ester - Physico-chemical Properties
Molecular Formula | C11H12BrNO2
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Molar Mass | 270.12 |
Density | 1.451 |
Boling Point | 361.1°C at 760 mmHg |
Flash Point | 172.2°C |
Vapor Presure | 2.11E-05mmHg at 25°C |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.562 |
6-Bromo-1,2,3,4-tetrahydro-2-quinolinecarboxylic acid methyl ester - Introduction
Methyl 6-bromo-1,2,3, is an organic compound. Its formula is C12H14BrNO2.
Nature:
-Appearance: colorless liquid
-Melting Point: Below Room Temperature
-Boiling point: about 220 degrees Celsius
-Density: about 1.45 g/ml
-Solubility: Soluble in some organic solvents, such as ethanol, acetone and esters.
Use:
methyl 6-bromo-1,2,3, is used as a valuable intermediate compound in organic synthesis and medicinal chemistry. It can be used to synthesize quinoline compounds, such as drugs, dyes and pesticides.
Preparation Method:
Methyl 6-bromo-1,2,3, is synthesized by the following steps:
1. First, quinoline is reacted with hydrobromic acid to obtain 6-bromo-1, 2,3, 4-tetrahydroquinoline.
2. Then, under alkaline conditions, 6-bromo-1, 2,3, 4-tetrahydroquinoline is reacted with methyl formate to produce the final product.
Safety Information:
- methyl 6-bromo-1,2,3, the need to operate in a well-ventilated place, and take appropriate personal protective measures, such as wearing protective gloves and goggles.
-It may be irritating to the skin and eyes and should be avoided.
-Keep away from fire and high temperature to avoid fire or explosion.
-When accidentally inhaled or ingested, seek medical attention immediately.
Last Update:2024-04-09 21:01:54